The history of Nihon Nohyaku Co, Ltd. comprises a major part of the history of Japan's agrochemical industry.
In the early 1920's, Furukawa Mining Co., Ltd. (now Furukawa Co., Ltd.) used a by-product of copper refining to successfully produce lead arsenate, the first agrochemical to be registered in Japan. This project was soon transferred to Asahi Denka Kogyo Co., Ltd(now ADEKA CORPORATION).
In 1928, the Agricultural Chemical Department of Asahi Denka Kogyo Co., Ltd.(now ADEKA CORPORATION) and Fujii Seiyaku Co., Ltd. merged to form Nihon Nohyaku Co., Ltd., Japan's first agrochemical manufacturing company.
For nearly 80 years, Nihon Nohyaku has been a leader in the Japanese agrochemical industry. The company has been developing agricultural technology and applying it toward the expansion of its business to include such sectors as pharmaceuticals, fine chemicals, environmentally safe chemicals, and gardening.

Okochi Memorial Technology Award- 1976- awarded for Fuji-One
1986- awarded for malotilate
1988- awarded for Applaud 
Secretary of Chemical Technology Agency Award- 1990- awarded for Applaud

Purple Medal of Honor- 1986- awarded for Fuji-One
1992- awarded for Applaud
| 1928 | Nihon Nohyaku Co., Ltd. established (Head Office, Osaka) |
|---|---|
| 1930 | Disease and Insect Research Farm opened in Kawachi |
| 1934 | Tsukuda Plant (now Osaka Plant) constructed |
| 1934 | Kyushu Liaison Office (now Fukuoka Branch) opened |
| 1938 | Manchuria Nohyaku Co., Ltd. established |
| 1942 | Korean Nohyaku Co., Ltd. established |
| 1953 | Tokyo Plant constructed in Toda, Saitama |
| 1955 | Hokkaido Liaison Office (now Sapporo Branch) opened |
| 1956 | Chemical Research Laboratory constructed in Osaka |
| 1959 | Head Office relocated to Tokyo |
| 1961 | Daiichi Nohyaku Co., Ltd. established in Okinawa |
| 1964 | Nagoya Liaison Office opened |
| 1969 | Saga Plant constructed |
| 1969 | Agricultural Chemicals of Malaysia (ACM) established in Malaysia |
| 1973 | Safety Research Center constructed in Kawachinagano, Osaka |
| 1974 | Nichino Ryokka Co., Ltd. established |
| 1975 | Fuji-One(isoprothiolane) launched |
| 1976 | Kashima Plant constructed in Kamisu, Ibaraki |
| 1979 | Tohoku Sales Office (now Sendai Branch) opened |
| 1983 | Fukushima Plant constructed in Nihonmatsu, Fukushima |
| 1984 | Tokyo Plant closed due to introduction of the bullet train |
| 1984 | Applaud(buprofezin) launched |
| 1985 | Nichino Rec Co., Ltd. established |
| 1985 | Moncut(flutolanil) launched |
| 1985 | Kantec (malotilate) launched |
| 1989 | Japan House Tech Co., Ltd. (now Nichino Service Co., Ltd.) established |
| 1990 | Japan EcoTech Co., Ltd. established |
| 1991 | Danitron(fenpyroximate) launched |
| 1991 | Pharmaceutical Research Center constructed in Kawachinagano, Osaka |
| 1992 | London Office (now Nichino Europe Co. Ltd.) opened |
| 1992 | Naganuma Nursery opened in Hokkaido |
| 1993 | Research Center (1st stage) constructed in Kawachinagano, Osaka |
| 1994 | Astat (lanoconazole) launched for ethical use |
| 1995 | New York Office (now Nichino America Inc.) opened |
| 1995 | Research Center construction completed in Kawachinagano, Osaka |
| 1996 | Taiwan Nihon Nohyaku Co., Ltd. established |
| 1998 | Malaysia Office opened |
| 1999 | Ecopart(pyraflufen-ethyl) launched |
| 1999 | Thunderbolt(pyraflufen-ethyl mixture) launched |
| 2000 | Malaysia Office closed, and Bangkok Office opened |
| 2001 | Nichino America, Inc. established |
| 2002 | A portion of Tomono Agrica's business acquired |
| 2002 | Mitsubishi Chemical Corp.'s plant protection business acquired |
| 2002 | Nagoya Branch integrated into Tokyo and Osaka Branch |
| 2003 | V-Get (tiadinil) launched |
| 2005 | Shanghai Office opened |
| 2005 | Lulicon (luliconazole) launched |
| 2007 | Zespart, Windom (lanoconazole) launched for OTC use |
| 2007 | Phoenix (flubendiamide) launched |
| 2007 | Nichino Europe Co.,Ltd established |
| 2007 | Prac-tic (pyriprole) launched |
| 2008 | Multi-Purpose Plant constructed in Kashima Plant |
| 2010 | Axel (metaflumizone) launched in Japan |